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Article

Molecular profiling of sinonasal undifferentiated carcinoma.

Head & neck - 1 Jan 2014

Gelbard Alexander, Hale Katherine S, Takahashi Yoko, Davies Michael, Kupferman Michael E, El-Naggar Adel K, Myers Jeffrey N, Hanna Ehab Y

Abstract excerpt

BACKGROUND: Sinonasal undifferentiated carcinoma (SNUC) remains a poorly characterized malignancy at both the clinical and molecular level, and, consequently, the optimal treatment strategy remains undefined. METHODS: We used a mass spectroscopy-based approach (Sequenom) to evaluate 95 hallmark single nucleotide variations (SNVs) within 12 oncogenes or tumor suppressor genes (AKT, BRAF, CDK4, Beta-catenin,...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Paranasal Sinus Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23633104
DOI: 10.1002/hed.23267
PMCID: PMC3874284

Genes

BRAF
CDK4
EGFR
JAK2
KIT
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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