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Article

[TDP-43 proteinopathies: ALS and frontotemporal dementias].

Fortschritte der Neurologie-Psychiatrie - 1 Aug 2009

Prudlo J

Abstract excerpt

Both, amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U), and their combination (FTLD-U/MND) are principally sporadic diseases that are rarely familial. Cytoplasmic ubiquitinated proteinaceous inclusions in motor and extra-motor neurons are the pathological hallmark of all three forms. In 2006, the TAR DNA-binding protein of 43 kDa (TDP-43) was...

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Identifiers

PMID: 19685386
DOI: 10.1055/s-0028-1109602

Genes

TARDBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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