Article
Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling.
Immunological reviews - 1 Jan 2010
Manzo Antonio, Bombardieri Michele, Humby Frances, Pitzalis Costantino
Abstract excerpt
Rheumatoid arthritis is a chronic systemic inflammatory disease primarily affecting the synovium of diarthrodial joints. Despite the currently unknown etiology, overwhelming evidence indicates that both innate and adaptive immunity play a central role in disease pathogenesis. In this review, we c...
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