Article
CD8(+) T cells in human autoimmune arthritis: the unusual suspects.
Nature reviews. Rheumatology - 1 Jul 2016
Petrelli Alessandra, van Wijk Femke
Abstract excerpt
CD8(+) T cells are key players in the body's defence against viral infections and cancer. To date, data on the role of CD8(+) T cells in autoimmune diseases have been scarce, especially when compared with the wealth of research on CD4(+) T cells. However, growing evidence suggests that CD8(+) T-cell homeostasis is impaired in human autoimmune diseases. The contribution of CD8(+) T cells to autoimmune arthritis is...
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