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Article

Lack of p47(phox) in Akita Diabetic Mice Is Associated with Interstitial Pneumonia, Fibrosis, and Oral Inflammation.

The American journal of pathology - 1 Mar 2016

Zamakhchari Mai F, Sima Corneliu, Sama Kishore, Fine Noah, Glogauer Michael, Van Dyke Thomas E, Gyurko Robert

Abstract excerpt

Excess reactive oxygen species production is central to the development of diabetic complications. The contribution of leukocyte reactive oxygen species produced by the NADPH oxidase to altered inflammatory responses associated with uncontrolled hyperglycemia is poorly understood. To get insight into the role of phagocytic superoxide in the onset of diabetic complications, we used a model of periodontitis in mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26747235
DOI: 10.1016/j.ajpath.2015.10.026
PMCID: PMC4816692

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