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Probe-free allele-specific copy number detection and analysis of tumors.

Analytical biochemistry - 15 Mar 2016

Zhu Ailin, Guan Xiaowei, Gu Xinbin, Xie Guiqin

Abstract excerpt

Cancer development and progression frequently involve nucleotide mutations as well as amplifications and deletions of genomic segments. Quantification of allele-specific copy number is an important step in characterizing tumor genomes for precision medicine. Despite advances in approaches to high-throughput genomic DNA analysis, inexpensive and simple methods for analyzing complex nucleotide and copy number...

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PMID: 26743720
DOI: 10.1016/j.ab.2015.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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