Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients.

PloS one - 1 Jan 2015

Stadler Julia, Eder Johanna, Pratscher Barbara, Brandt Sabine, Schneller Doris, Müllegger Robert, Vogl Claus, Trautinger Franz, Brem Gottfried, Burgstaller Joerg P

Abstract excerpt

Cell-free circulating tumor DNA in the plasma of cancer patients has become a common point of interest as indicator of therapy options and treatment response in clinical cancer research. Especially patient- and tumor-specific single nucleotide variants that accurately distinguish tumor DNA from wild type DNA are promising targets. The reliable detection and quantification of these single-base DNA variants is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Copy Number Variations
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to Melanoma

Share to Neoplasm Staging

Share to Proto-Oncogene Proteins B-raf

Share to PTEN Phosphohydrolase

Share to Real-Time Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 26562020
DOI: 10.1371/journal.pone.0142273
PMCID: PMC4642939

Genes

BRAF
NRAS
PTEN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients.PMID 26562020Read ↗

Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay.Semantic proximity Read ↗

Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags.Semantic proximity Read ↗

Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baitsSemantic proximity Read ↗

Single-Tube, Switched Temperature Amplicon Barcoding for Multiplex Detection of Rare Mutations in Circulating Tumor DNA.Semantic proximity Read ↗

Digital RNA sequencing using unique molecular identifiers enables ultrasensitive RNA mutation analysis.Semantic proximity Read ↗

Artificial base mismatches-mediated PCR (ABM-PCR) for detecting clinically relevant single-base mutationsSemantic proximity Read ↗

Highly sensitive and specific real-time PCR by employing serial invasive reaction as a sequence identifier for quantifying EGFR mutation abundance in cfDNA.Semantic proximity Read ↗

Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules.Semantic proximity Read ↗

Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA moleculesSemantic proximity Read ↗

Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancySemantic proximity Read ↗

Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNASemantic proximity Read ↗

An ultrasensitive method for detecting mutations from short and rare cell-free DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.