Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of molecular inversion probe performance for allele copy number determination.

Genome biology - 1 Jan 2007

Wang Yuker, Moorhead Martin, Karlin-Neumann George, Wang Nicholas J, Ireland James, Lin Steven, Chen Chunnuan, Heiser Laura M, Chin Koei, Esserman Laura, Gray Joe W, Spellman Paul T, Faham Malek

Abstract excerpt

We have developed a new protocol for using molecular inversion probes to accurately and specifically measure allele copy number. The new protocol provides for significant improvements, including the reduction of input DNA (from 2 mug) by more than 25-fold (to 75 ng total genomic DNA), higher overall precision resulting in one order of magnitude lower false positive rate, and greater dynamic range with accurate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Inversion

Share to False Positive Reactions

Share to Loss of Heterozygosity

Share to Molecular Probes

Share to Polymerase Chain Reaction

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 18028543
DOI: 10.1186/gb-2007-8-11-r246
PMCID: PMC2258201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of molecular inversion probe performance for allele copy number determination.PMID 18028543Read ↗

Molecular inversion probe assay for allelic quantitation.Semantic proximity Read ↗

Allele quantification using molecular inversion probes (MIP).Semantic proximity Read ↗

Molecular inversion probe assay.Semantic proximity Read ↗

Practical guidelines for interpreting copy number gains detected by high-resolution array in routine diagnosticsSemantic proximity Read ↗

Multiplexed genotyping with sequence-tagged molecular inversion probes.Semantic proximity Read ↗

Molecular inversion probes: a novel microarray technology and its application in cancer research.Semantic proximity Read ↗

A survey of current methods to detect and genotype inversions.Semantic proximity Read ↗

Ultrasensitive Quantitation of Genomic Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms.Semantic proximity Read ↗

Epiallele quantification using molecular inversion probes.Semantic proximity Read ↗

Ultrasensitive Detection of Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms.Semantic proximity Read ↗

Probe-free allele-specific copy number detection and analysis of tumors.Semantic proximity Read ↗

Sensitive quantification of somatic mutations using molecular inversion probes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.