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Article

Gene Polymorphism of Toll-Like Receptors and Lung Function at Five to Seven Years of Age after Infant Bronchiolitis.

PloS one - 1 Jan 2016

Lauhkonen Eero, Koponen Petri, Vuononvirta Juho, Teräsjärvi Johanna, Nuolivirta Kirsi, Toikka Jyri O, Helminen Merja, He Qiushui, Korppi Matti

Abstract excerpt

AIM: Toll-like receptors (TLR) play a crucial role in innate immunity, protecting the host from pathogens such as viruses. Genetic variations in TLRs have been associated with the severity of viral bronchiolitis in infancy and with the later occurrence of post-bronchiolitis asthma. The aim of the present study was to evaluate if there are any exploratory associations between TLR gene polymorphisms and lung...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26741133
DOI: 10.1371/journal.pone.0146526
PMCID: PMC4704821

Genes

TLR4
TLR6
TLR7
TLR2
TLR1
TLR10
TLR3
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene Polymorphism of Toll-Like Receptors and Lung Function at Five to Seven Years of Age after Infant Bronchiolitis.PMID 26741133Read ↗

Risk factors for irreversible airway obstruction after infant bronchiolitis.Semantic proximity Read ↗

Toll-like receptor 10 rs4129009 gene polymorphism is associated with post-bronchiolitis lung function in adolescence.Semantic proximity Read ↗

IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age.Semantic proximity Read ↗

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.Semantic proximity Read ↗

Polymorphism in the gene encoding toll-like receptor 10 may be associated with asthma after bronchiolitis.Semantic proximity Read ↗

Toll-like receptor 1 and 10 gene polymorphisms are linked to postbronchiolitis asthma in adolescence.Semantic proximity Read ↗

Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age.Semantic proximity Read ↗

IL-10 gene polymorphism is associated with preschool atopy and early-life recurrent wheezing after bronchiolitis in infancy.Semantic proximity Read ↗

Toll-like receptor 3 L412F polymorphisms in infants with bronchiolitis and postbronchiolitis wheezing.Semantic proximity Read ↗

Genetic variations in Toll-like receptors 4 or 7 were not linked to post-bronchiolitis lung function in adolescence.Semantic proximity Read ↗

IL17RA variations showed no associations with post-bronchiolitis asthma or lung function.Semantic proximity Read ↗

Association of TLR polymorphisms with bronchopulmonary dysplasia.Semantic proximity Read ↗

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