Article
Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age.
Acta paediatrica (Oslo, Norway : 1992) - 1 Mar 2022
Riikonen Riikka, Teräsjärvi Johanna, Lauhkonen Eero, Nuolivirta Kirsi, He Qiushui, Korppi Matti
Abstract excerpt
AIM: Interleukin (IL) 1 receptor-like 1, encoded by the IL1RL1 gene, is a receptor for IL-33. In European birth cohorts, IL1RL1 rs102082293, rs10204137 (rs4988955), rs13424006 and rs13431828 (rs13048661) variations were associated with asthma at school age. In a Dutch multi-centre study, IL1RL1 variation was associated with severe bronchiolitis. We evaluated the associations of these five IL1RL1...