Article
Polymorphism in the gene encoding toll-like receptor 10 may be associated with asthma after bronchiolitis.
Scientific reports - 7 Jun 2017
Törmänen Sari, Korppi Matti, Teräsjärvi Johanna, Vuononvirta Juho, Koponen Petri, Helminen Merja, He Qiushui, Nuolivirta Kirsi
Abstract excerpt
Toll-like receptors (TLRs) recognise microbes that contribute to the severity of bronchiolitis and the subsequent risk of asthma. We evaluated whether post-bronchiolitis asthma was associated with polymorphisms in the TLR3 rs3775291, TLR4 rs4986790, TLR7 rs179008, TLR8 rs2407992, TLR9 rs187084, and TLR10 genes. The gene polymorphisms were studied at the age of 6.4 years (mean) in 135 children...