Article
Toll-like receptor 3 L412F polymorphisms in infants with bronchiolitis and postbronchiolitis wheezing.
The Pediatric infectious disease journal - 1 Sept 2012
Nuolivirta Kirsi, He Qiushui, Vuononvirta Juho, Koponen Petri, Helminen Merja, Korppi Matti
Abstract excerpt
BACKGROUND: Innate immunity receptors play a critical role in host defense. In addition, the expression of Toll-like receptors (TLRs) has been connected to allergy and asthma. AIMS: : To evaluate the association between the TLR3 L412F polymorphism and viral findings, clinical characteristics and subsequent wheezing in young infants with bronchiolitis. METHODS: In all, 129 full-term infants hospitalized for...
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