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Article

IL-10 gene polymorphism is associated with preschool atopy and early-life recurrent wheezing after bronchiolitis in infancy.

Pediatric pulmonology - 1 Jan 2017

Korppi Matti, Nuolivirta Kirsi, Lauhkonen Eero, Holster Annukka, Teräsjärvi Johanna, Vuononvirta Juho, Helminen Merja, He Qiushui, Koponen Petri

Abstract excerpt

BACKGROUND: Variations in the genes that regulate innate immunity responses may be associated with susceptibility to asthma or atopy after early-life bronchiolitis. The aim of this study was to evaluate the association between four different polymorphisms of the IL-10 gene at rs1800871, rs1800872, rs1800890, and rs1800896, either alone or in combination, and post-bronchiolitis asthma or allergies at 5-7 years of...

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Identifiers

PMID: 27228545
DOI: 10.1002/ppul.23489

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