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Article

Associations Between Self-Reported and Objectively Recorded Early Life Stress, FKBP5 Polymorphisms, and Depressive Symptoms in Midlife.

Biological psychiatry - 1 Dec 2016

Lahti Jari, Ala-Mikkula Heidi, Kajantie Eero, Haljas Kadri, Eriksson Johan G, Räikkönen Katri

Abstract excerpt

BACKGROUND: FK506-binding protein 51 is involved in hypothalamic-pituitary-adrenal axis regulation. Single nucleotide polymorphisms (SNPs) in the FKBP5 gene have been shown to interact with retrospectively self-reported early life stress (ELS) in patients with psychiatric disorders. We examined interactions between three selected FKBP5 SNPs and self-reported and objectively recorded ELS in relation to depressive...

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Identifiers

PMID: 26740367
DOI: 10.1016/j.biopsych.2015.10.022

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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