Article
Early Life Stress, FKBP5 Polymorphisms, and Quantitative Glycemic Traits.
Psychosomatic medicine - 1 Jun 2017
Suarez Anna, Lahti Jari, Kajantie Eero, Eriksson Johan G, Räikkönen Katri
Abstract excerpt
OBJECTIVE: Early life stress (ELS) has been shown to influence health later in life. Functioning of the hypothalamic-pituitary-adrenal axis, regulated partly by FKBP5 gene, may moderate these effects. We examined whether FKBP5 single-nucleotide polymorphisms (SNPs) interact with ELS on Type 2 diabetes, cardiovascular disease, and quantitative glycemic traits. METHODS: A total of 1728 Helsinki Birth Cohort Study...
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