Article
Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses.
Brain research - 12 Mar 2004
Yu Liqun, Frith Martin C, Suzuki Yutaka, Peterfreund Robert A, Gearan Tom, Sugano Sumio, Schwarzschild Michael A, Weng Zhiping, Fink J Stephen, Chen Jiang-Fan
Abstract excerpt
The adenosine A(2A) receptor (A(2A)R) is abundantly expressed in brain and emerging as an important therapeutic target for Parkinson's disease and potentially other neuropsychiatric disorders. To understand the molecular mechanisms of A(2A)R gene expression, we have characterized the genomic organization of the mouse and human A(2A)R genes by molecular and bioinformatic analyses. Three new exons (m1A, m1B and...
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