Article
A proposal for improvement of genotyping performance for ethnically homogeneous population using DNA microarray.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2015
Fukushima Arika, Paul Topon, Shingaki Ryusei, Koiso Takashi, Umeno Shinya, Ueno Ken
Abstract excerpt
DNA microarray is used to determine the genotypes of several hundred thousand to several million SNPs (Single Nucleotide Polymorphisms) on multiple samples at a time. In the conventional method of genotyping using DNA microarray, it is assumed that each SNP has three types of genotypes: two homozygous and one heterozygous genotypes. However, in an ethnically homogeneous population, there are cases when all the...
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