Article
Microarrays for personalized genomic medicine.
Advances in clinical chemistry - 1 Jan 2010
Lam Ching-Wan, Lau Kin-Chong, Tong Sui-Fan
Abstract excerpt
The combination of single nucleotide polymorphisms (SNPs) database and high-density SNP array allows the use of SNPs as informative polymorphic markers for Mendelian diseases with complex traits efficiently. With the high-density and high-resolution SNP arrays, we can detect even the smallest structural changes that would have been missed with conventional low-density cytogenetic techniques for prognostic and...
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