Article
A new genotype calling method for affymetrix SNP arrays.
Journal of bioinformatics and computational biology - 1 Dec 2011
Fu Bilin, Xu Jin
Abstract excerpt
Current genotype-calling methods such as Robust Linear Model with Mahalanobis Distance Classifier (RLMM) and Corrected Robust Linear Model with Maximum Likelihood Classification (CRLMM) provide accurate calling results for Affymetrix Single Nucleotide Polymorphisms (SNP) chips. However, these methods are computationally expensive as they employ preprocess procedures, including chip data normalization and other...
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