Inhibition ofStreptococcus mutansbiofilm formation by strategies targeting the metabolism of exopolysaccharides

Abstract excerpt

Dental caries is one of the most prevalent and costly biofilm-associated infectious diseases affecting most of the world’s population. In particular, dental caries is driven by dysbiosis of the dental biofilm adherent to the enamel surface. Specific types of acid-producing bacteria, especially Streptococcus mutans, colonize the dental surface and cause damage to the hard tooth structure in the presence of...