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Triethylene Glycol Up-Regulates Virulence-Associated Genes and Proteins in Streptococcus mutans

7 Nov 2016

Abstract excerpt

Triethylene glycol dimethacrylate (TEGDMA) is a diluent monomer used pervasively in dental composite resins. Through hydrolytic degradation of the composites in the oral cavity it yields a hydrophilic biodegradation product, triethylene glycol (TEG), which has been shown to promote the growth of Streptococcus mutans, a dominant cariogenic bacterium. Previously it was shown that TEG up-regulated gtfB, an important...

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PMID: 27820867
DOI: 10.1371/journal.pone.0165760

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