Article
A gender-specific association of CNV at 6p21.3 with NPC susceptibility.
Human molecular genetics - 15 Jul 2011
Tse Ka-Po, Su Wen-Hui, Yang Min-lee, Cheng Hsiao-Yun, Tsang Ngan-Ming, Chang Kai-Ping, Hao Sheng-Po, Yao Shugart Yin, Chang Yu-Sun
Abstract excerpt
Copy number variations (CNVs), a major source of human genetic polymorphism, have been suggested to have an important role in genetic susceptibility to common diseases such as cancer, immune diseases and neurological disorders. Nasopharyngeal carcinoma (NPC) is a multifactorial tumor closely associated with genetic background and with a male preponderance over female (3:1). Previous genome-wide association...
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