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Genomic copy number variations in three Southeast Asian populations.

Human mutation - 1 Jul 2010

Ku Chee-Seng, Pawitan Yudi, Sim Xueling, Ong Rick T H, Seielstad Mark, Lee Edmund J D, Teo Yik-Ying, Chia Kee-Seng, Salim Agus

Abstract excerpt

Research on the role of copy number variations (CNVs) in the genetic risk of diseases in Asian populations has been hampered by a relative lack of reference CNV maps for Asian populations outside the East Asians. In this article, we report the population characteristics of CNVs in Chinese, Malay, and Asian Indian populations in Singapore. Using the Illumina Human 1M Beadchip array, we identify 1,174 CNV loci in...

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PMID: 20506136
DOI: 10.1002/humu.21287

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