Article
Molecular characteristics of pediatric nasopharyngeal carcinoma using whole-exome sequencing.
Oral oncology - 1 Dec 2022
Wu Bian, Shen Liangfang, Peng Gang, Li Yingqiang, Zhou Zhiyuan, Li Jingao, Huang Xiaodong, Zhou Qin, Jiang Hongguo, Huang Jing, Ding Qian, Zhang Zhanjie, Qin You, Hong Xiaohua, Shi Liangliang, Zou Zhenwei, Yao Jing, Zhang Jing, Liu Danni, Wan Chao, Wu Gang, Song Lele, Chen Shifu, Yi Junlin, Yang Kunyu
Abstract excerpt
OBJECTIVES: While a number of genetic and epigenetic events contributing to adult nasopharyngeal carcinomas (aNPC) development has been established, the scarcity of pediatric nasopharyngeal carcinoma (pNPC) hinders the understanding of the biology of the disease and rational treatment approach. We aim to identify the molecular characteristics of pNPC. MATERIALS AND METHODS: pNPC primary tumors with paired blood...
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