Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Colorectal cancer: role of commensal bacteria and bystander effects

2 Nov 2015

Abstract excerpt

For years the human microbiota has been implicated in the etiology of colorectal cancer (CRC). However, identifying the molecular mechanisms for how aneuploidy and chromosomal instability (CIN) arise in sporadic and colitis-associated CRC has been difficult. In this Addendum we review recent work from our laboratory that explore mechanisms by which intestinal commensals polarize colon macrophages to an M1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Immunotherapy and Biomarkers
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26727419
DOI: 10.1080/19490976.2015.1103426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Colorectal cancer: role of commensal bacteria and bystander effectsPMID 26727419Read ↗

It takes a village: microbiota, parainflammation, paligenosis and bystander effects in colorectal cancer initiationSemantic proximity Read ↗

<i>Enterococcus faecalis</i> Induces Aneuploidy and Tetraploidy in Colonic Epithelial Cells through a Bystander EffectSemantic proximity Read ↗

The chromosomal instability pathway in colon cancer.Semantic proximity Read ↗

Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesisSemantic proximity Read ↗

Evidence from Animal Models: Is a Restricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury?Semantic proximity Read ↗

Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury.Semantic proximity Read ↗

Genomic instability and colon cancer.Semantic proximity Read ↗

Mechanistic dissection unmasks colibactin as a prevalent mutagenic driver of cancer.Semantic proximity Read ↗

Folate deficiency induces mitotic aberrations and chromosomal instability by compromising the spindle assembly checkpoint in cultured human colon cellsSemantic proximity Read ↗

Colon Macrophages Polarized by Commensal Bacteria Cause Colitis and Cancer through the Bystander EffectSemantic proximity Read ↗

Differential effects of aneuploidy on growth and differentiation in human intestinal stem cellsSemantic proximity Read ↗

Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.