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Article

Alzheimer's disease susceptibility genes modify the risk of Parkinson disease and Parkinson's disease-associated cognitive impairment.

Neuroscience letters - 11 Jun 2018

Fang Lu, Tang Bei-Sha, Fan Kuan, Wan Chang-Min, Yan Xin-Xiang, Guo Ji-Feng

Abstract excerpt

The pathogenic mechanism underlying Parkinson's disease (PD) and PD- Cognitive impairment (CI) remains elusive. Its potential link to the risk factors in Alzheimer's disease (AD) is unclear. In this study, we analyzed 16 CE-associated single nucleotide polymorphisms (SNPs) in twelve genes in a Chinese cohort of 450 PD cases and 449 controls. Among our 298 cases clinically evaluated for CI, 113 cases did not show...

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Source

Identifiers

PMID: 29698690
DOI: 10.1016/j.neulet.2018.04.042

Genes

APOE
BDNF
CLU

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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