Article
Genetic association between CARD9 variants and inflammatory bowel disease was not replicated in a Chinese Han population.
International journal of clinical and experimental pathology - 1 Jan 2015
Wang Zhengting, Fan Rong, Wang Lei, Zhou Jie, Zheng Sichang, Hu Shurong, Chen Mengmeng, Zhang Tianyu, Lin Yun, Zhang Maochen, Zhong Jie
Abstract excerpt
OBJECTIVE: In order to investigate whether CARD9 gene is associated with IBD in Chinese Han population, we replicated 2 SNPs of CARD9 which have been reported to be significantly associated with IBD. METHODS: Two SNPs were genotyped using polymerase chain reaction with sequence-specific primers in 288 patients (232 CD patients, 56 UC patients) and 274 controls. RESULTS: The frequencies and distributions of...
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