Article
Association of CARD8 with inflammatory bowel disease in Koreans.
Journal of human genetics - 1 Mar 2011
Yang Suk-Kyun, Kim Hyeri, Hong Myunghee, Lim Jiyoung, Choi Eunkyoung, Ye Byong Duk, Park Soo-Kyung, Song Kyuyoung
Abstract excerpt
Caspase recruitment domain (CARD)-containing protein 8 (CARD8) is a potential candidate risk gene for inflammatory bowel disease (IBD) because of its role as a component of the NALP3 inflammasome and as an inhibitor of nuclear factor-kappa B. Previous studies examining the association of a CARD8...
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