Article
A functional variant in the CARD4 gene and risk of premature coronary heart disease.
International journal of immunogenetics - 1 Aug 2006
El Mokhtari N E, Ott S J, Nebel A, Simon R, Schreiber S
Abstract excerpt
Infection and innate immunity have been suggested as playing an important role in the pathogenesis of atherosclerosis. The recently discovered pattern-recognition receptor (PRR) proteins initiate signalling after host-pathogen interactions and several PRRs, especially the Toll-like receptor 4 (TL...
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