Article
Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals.
The British journal of psychiatry : the journal of mental science - 1 Aug 2017
Rivera Margarita, Locke Adam E, Corre Tanguy, Czamara Darina, Wolf Christiane, Ching-Lopez Ana, Milaneschi Yuri, Kloiber Stefan, Cohen-Woods Sarah, Rucker James, Aitchison Katherine J, Bergmann Sven, Boomsma Dorret I, Craddock Nick, Gill Michael, Holsboer Florian, Hottenga Jouke-Jan, Korszun Ania, Kutalik Zoltan, Lucae Susanne, Maier Wolfgang, Mors Ole, Müller-Myhsok Bertram, Owen Michael J, Penninx Brenda W J H, Preisig Martin, Rice John, Rietschel Marcella, Tozzi Federica, Uher Rudolf, Vollenweider Peter, Waeber Gerard, Willemsen Gonneke, Craig Ian W, Farmer Anne E, Lewis Cathryn M, Breen Gerome, McGuffin Peter
Abstract excerpt
BackgroundDepression and obesity are highly prevalent, and major impacts on public health frequently co-occur. Recently, we reported that having depression moderates the effect of the FTO gene, suggesting its implication in the association between depression and obesity.AimsTo confirm these findings by investigating the FTO polymorphism rs9939609 in new cohorts, and subsequently in a meta-analysis.MethodThe...
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