Article
Electrostatic Repulsion during Ferritin Assembly and Its Screening by Ions.
Biochemistry - 26 Jan 2016
Sato Daisuke, Takebe Satsuki, Kurobe Atsushi, Ohtomo Hideaki, Fujiwara Kazuo, Ikeguchi Masamichi
Abstract excerpt
Escherichia coli non-heme-binding ferritin A (EcFtnA) is a spherical cagelike protein that is composed of 24 identical subunits. EcFtnA dissociates into 2-mers under acidic conditions and can reassemble into the native structure when the pH is increased. To understand how electrostatic interactions influence the assembly reaction, the dependence of the process on ionic strength and pH was investigated. The...
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