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Article

Study of IRF6 and 8q24 region in non-syndromic oral clefts in the Brazilian population.

Oral diseases - 1 Apr 2016

de Souza L T, Kowalski T W, Ferrari J, Monlléo I L, Ribeiro E M, de Souza J, Fett-Conte A C, de Araujo T K, Gil-da-Silva-Lopes V L, Ribeiro-Dos-Santos Â K C, dos Santos S E B, Félix T M

Abstract excerpt

OBJECTIVES: We investigated the association between non-syndromic oral cleft and variants in IRF6 (rs2235371 and rs642961) and 8q24 region (rs987525) according to the ancestry contribution of the Brazilian population. SUBJECTS AND METHODS: Subjects with oral cleft (CL, CLP, or CP) and their parents were selected from different geographic regions of Brazil. Polymorphisms were genotyped using a TaqMan assay and...

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PMID: 26714022
DOI: 10.1111/odi.12432

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