Article
Quantitative analysis of CagA type IV secretion by Helicobacter pylori reveals substrate recognition and translocation requirements
29 Dec 2015
Abstract excerpt
Bacterial type IV secretion systems are protein transporters with a remarkable diversity of substrates and substrate recognition mechanisms. Type IV-secreted proteins often contain C-terminal secretion signals, but may also require other regions for recognition as secretory substrates, or for full secretion efficiency. For example, type IV secretion of CagA, a major pathogenicity factor of the human gastric...
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