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Article

Membrane-Bound PenA β-Lactamase of Burkholderia pseudomallei.

Antimicrobial agents and chemotherapy - 28 Dec 2015

Randall Linnell B, Dobos Karen, Papp-Wallace Krisztina M, Bonomo Robert A, Schweizer Herbert P

Abstract excerpt

Burkholderia pseudomallei is the etiologic agent of melioidosis, a difficult-to-treat disease with diverse clinical manifestations. β-Lactam antibiotics such as ceftazidime are crucial to the success of melioidosis therapy. Ceftazidime-resistant clinical isolates have been described, and the most common mechanism is point mutations affecting expression or critical amino acid residues of the chromosomally encoded...

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PMID: 26711764
DOI: 10.1128/AAC.02444-15
PMCID: PMC4775993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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