Article
Burkholderia cenocepacia J2315 acyl carrier protein: a potential target for antimicrobials' development?
Microbial pathogenesis - 1 Jan 2000
Sousa Sílvia A, Ramos Christian G, Almeida Filipe, Meirinhos-Soares Luís, Wopperer Julia, Schwager Stephan, Eberl Leo, Leitão Jorge H
Abstract excerpt
This work describes the isolation and characterization of an acyl carrier protein (ACP) mutant from Burkholderia cenocepacia J2315, a strain of the Burkholderia cepacia complex (Bcc). Bcc comprises at least 9 species that emerged as opportunistic pathogens able to cause life-threatening infections, particularly severe among cystic fibrosis patients. Bacterial ACPs are the donors of the acyl moiety involved in the...
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