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Article

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.

Molecular & cellular proteomics : MCP - 1 Apr 2015

Vander Broek Charles W, Chalmers Kevin J, Stevens Mark P, Stevens Joanne M

Abstract excerpt

Burkholderia pseudomallei is an intracellular pathogen and the causative agent of melioidosis, a severe disease of humans and animals. One of the virulence factors critical for early stages of infection is the Burkholderia secretion apparatus (Bsa) Type 3 Secretion System (T3SS), a molecular syringe that injects bacterial proteins, called effectors, into eukaryotic cells where they subvert cellular functions to...

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Identifiers

PMID: 25635268
DOI: 10.1074/mcp.M114.044875
PMCID: PMC4390269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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