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Article

Regulation of bone metabolism by Wnt signals.

Journal of biochemistry - 1 Apr 2016

Kobayashi Yasuhiro, Uehara Shunsuke, Udagawa Nobuyuki, Takahashi Naoyuki

Abstract excerpt

Wnt ligands play a central role in the development and homeostasis of various organs through β-catenin-dependent and -independent signalling. The crucial roles of Wnt/β-catenin signals in bone mass have been established by a large number of studies since the discovery of a causal link between mutations in the low-density lipoprotein receptor-related protein 5 (Lrp5) gene and alternations in human bone mass. The...

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Identifiers

PMID: 26711238
DOI: 10.1093/jb/mvv124
PMCID: PMC4885935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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