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Involvement of the Wnt/β‐catenin signalling pathway in heterotopic ossification and ossification‐related diseases

1 Sept 2024

Abstract excerpt

Heterotopic ossification (HO) is a pathological condition characterized by the formation of bone within soft tissues. The development of HO is a result of abnormal activation of the bone formation programs, where multiple signalling pathways, including Wnt/β-catenin, BMP and hedgehog signalling, are involved. The Wnt/β-catenin signalling pathway, a conserved pathway essential for various fundamental activities,...

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PMID: 39320014
DOI: 10.1111/jcmm.70113

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