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Article

Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas.

Melanoma research - 1 Apr 2016

Vazquez Vinicius de Lima, Vicente Anna L, Carloni Adriana, Berardinelli Gustavo, Soares Paula, Scapulatempo Cristovam, Martinho Olga, Reis Rui M

Abstract excerpt

Acral lentiginous melanoma (ALM) is the less common subtype with singular characterization. TERT (human telomerase reverse transcriptase) promoter mutations have being described as recurrent in melanomas and infrequent in ALM, but their real incidence and clinical relevance is unclear. The objectives of this study were to describe the prevalence of TERT promoter mutations in ALM, and correlate with the molecular...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Melanoma, Cutaneous Malignant

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 26709572
DOI: 10.1097/CMR.0000000000000222

Genes

TERT
KIT
PDGFRA
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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