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Article

Sperm DNA Methylation: Not a Vehicle for Dietary Reprogramming of Offspring?

Developmental cell - 21 Dec 2015

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Abstract excerpt

Reporting in Developmental Cell, Shea et al. (2015) show, using an inbred mouse strain, that "epivariation"-stochastic individual differences in DNA methylation-is a much greater contributor to the sperm methylome than is diet. They conclude that DNA methylation is not the mechanism underlying the dietary reprogramming of offspring phenotype.

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Identifiers

PMID: 26702825
DOI: 10.1016/j.devcel.2015.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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