Article
Group A Streptococcus emm3 strains induce early macrophage cell death.
Pathogens and disease - 1 Mar 2016
Dinis Márcia, Plainvert Céline, Longo Magalie, Guignot Julie, Gabriel Christelle, Poyart Claire, Fouet Agnès
Abstract excerpt
Group A Streptococcus (GAS) infections present high morbidity and mortality rates and consequently remain a significant health problem. The emm3 isolates induce more severe pathologies than all others. In this study, we tested, on a collection of invasive and non-invasive emm3 clinical isolates, whether in that genotype the invasive status of the strains affects the innate immune response. We show that...
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