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Article

The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.

PloS one - 1 Jan 2014

Dinis Márcia, Plainvert Céline, Kovarik Pavel, Longo Magalie, Fouet Agnès, Poyart Claire

Abstract excerpt

Group A Streptococcus (GAS) infections remain a significant health care problem due to high morbidity and mortality associated with GAS diseases, along with their increasing worldwide prevalence. Macrophages play a key role in the control and clearance of GAS infections. Moreover, pro-inflammatory cytokines production and GAS persistence and invasion are related. In this study we investigated the correlation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24991887
DOI: 10.1371/journal.pone.0101464
PMCID: PMC4081719

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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