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Article

Sputum mast cell subtypes relate to eosinophilia and corticosteroid response in asthma.

The European respiratory journal - 1 Apr 2016

Wang Gang, Baines Katherine J, Fu Juan Juan, Wood Lisa G, Simpson Jodie L, McDonald Vanessa M, Cowan Douglas C, Taylor D Robin, Cowan Jan O, Gibson Peter G

Abstract excerpt

Mast cells are a resident inflammatory cell of the airways, involved in both the innate and adaptive immune response. The relationship between mast cells and inflammatory phenotypes and treatment response of asthma is not clear.Clinical characteristics of subjects with stable asthma (n=55), inflammatory cell counts and gene expression microarrays in induced sputum were analysed. Sputum mast cell subtypes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26699720
DOI: 10.1183/13993003.01098-2015

Genes

CPA3
TPSAB1
CMA1

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