Article
Revisiting the role of the mast cell in asthma.
Current opinion in pulmonary medicine - 1 Jan 2016
Andersson Cecilia, Tufvesson Ellen, Diamant Zuzana, Bjermer Leif
Abstract excerpt
PURPOSE OF REVIEW: In humans, mast cells are ubiquitously present in tissues adjacent to external environment and consequently have an important sentential role in host defence, homeostasis and repair. Their key role in allergen-mediated conditions has been recognized for many decades already. So far, therapies targeting mast cells offered clinical efficacy in allergic conditions except for asthma. More recently,...
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