Article
Asthma endotypes in flux: integrating type 1 and type 2 inflammation for biological therapy advancement.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Dec 2025
Polu Picheswara Rao, Bikki Vamsi Krishna
Abstract excerpt
OBJECTIVE: To synthesize current understanding of type 1 (T1) and type 2 (T2) asthma endotypes and evaluate how their integration can advance precision biological therapy selection for improved patient outcomes. DATA SOURCES: Comprehensive literature review of peer-reviewed articles from PubMed, Embase, and Cochrane databases focusing on asthma immunopathology, endotype characterization, biomarker development,...
Read the complete abstract on PubMedTopics
- Humans
- Asthma
- Biomarkers
- Biological Therapy
- Inflammation
- Precision Medicine
- Phenotype