Article
Running Exercise in Obese Pregnancies Prevents IL-6 Trans-signaling in Male Offspring.
Medicine and science in sports and exercise - 1 May 2016
Bae-Gartz Inga, Janoschek Ruth, Kloppe Cora-Sophia, Vohlen Christina, Roels Frederik, Oberthür Andre, Alejandre Alcazar Miguel Angel, Lippach Gregor, Muether Philipp S, Dinger Katharina, Ferrari Nina, Graf Christine, Dötsch Jörg, Hucklenbruch-Rother Eva
Abstract excerpt
PURPOSE: Maternal obesity is known to predispose the offspring to impaired glucose metabolism and obesity associated with low-grade inflammation and hypothalamic dysfunction. Because preventive approaches in this context are missing to date, we aimed to identify molecular mechanisms in the offspring that are affected by maternal exercise during pregnancy. METHODS: Diet-induced obese mouse dams were divided into a...
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