Article
Shared effects of genetic and intrauterine and perinatal environment on the development of metabolic syndrome.
PloS one - 1 Jan 2013
Vuguin Patricia M, Hartil Kirsten, Kruse Michael, Kaur Harpreet, Lin Chia-Lei Vivian, Fiallo Ariana, Glenn Alan Scott, Patel Avanee, Williams Lyda, Seki Yoshinori, Katz Ellen B, Charron Maureen J
Abstract excerpt
Genetic and environmental factors, including the in utero environment, contribute to Metabolic Syndrome. Exposure to high fat diet exposure in utero and lactation increases incidence of Metabolic Syndrome in offspring. Using GLUT4 heterozygous (G4+/-) mice, genetically predisposed to Type 2 Diabe...
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