Article
Chronic maternal inflammation or high-fat-feeding programs offspring obesity in a sex-dependent manner.
International journal of obesity (2005) - 1 Sept 2017
Dudele A, Hougaard K S, Kjølby M, Hokland M, Winther G, Elfving B, Wegener G, Nielsen A L, Larsen A, Nøhr M K, Pedersen S B, Wang T, Lund S
Abstract excerpt
BACKGROUND/OBJECTIVES: The current world-wide obesity epidemic partially results from a vicious circle whereby maternal obesity during pregnancy predisposes the offspring for accelerated weight gain and development of metabolic syndrome. Here we investigate whether low-grade inflammation, characteristic of the obese state, provides a causal role for this disastrous fetal programming in mice. METHODS: We exposed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.