Article

Early life stress reduces voluntary exercise and its prevention of diet-induced obesity and metabolic dysfunction in mice

2020-01-25

Abstract excerpt

The development of obesity-related metabolic syndrome (MetS) involves a complex interaction of genetic and environmental factors. One environmental factor found to be significantly associated with MetS is early life stress (ELS). We have previously reported on our mouse model of ELS, induced by neonatal maternal separation (NMS), that displays altered regulation of the hypothalamic-pituitary-adrenal (HPA) axis and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2d84d69b-6956-5910-8d13-8cef1f0e9946
DOI: 10.1101/2020.01.24.918805

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Early life stress reduces voluntary exercise and its prevention of diet-induced obesity and metabolic dysfunction in miceDOI 10.1101/2020.01.24.918805Read

Effects of early-life exposure to Western diet and voluntary exercise on adult activity levels, exercise physiology, and associated traits in selectively bred High Runner mice.Semantic proximity Read

Voluntary wheel running improves outcomes in an early life stress-induced model of urologic chronic pelvic pain syndrome in male miceSemantic proximity Read

Early Stress History Alters Serum Insulin‐Like Growth Factor‐1 and Impairs Muscle Mitochondrial Function in Adult Male RatsSemantic proximity Read

Differential effects of an obesogenic post-weaning diet on male and female behaviour in miceSemantic proximity Read

Sex-specific sequels of early life stress on serine/threonine kinase activity in visceral adipose tissue from obese miceSemantic proximity Read

Early Postnatal Nutrition Determines Adult Physical Activity and Energy Expenditure in Female MiceSemantic proximity Read

Maternal high-fat diet induces long-term obesity with sex-dependent metabolic programming of adipocyte differentiation, hypertrophy and dysfunction in the offspringSemantic proximity Read

BDNF-Val66Met variant and adolescent stress interact to promote susceptibility to anorexic behavior in mice.Semantic proximity Read

Effects of early-life stress on peripheral and central mitochondria in male mice across agesSemantic proximity Read

Early-Life Effects on Adult Physical Activity: Concepts, Relevance, and Experimental ApproachesSemantic proximity Read

Animal Models and Their Contribution to Our Understanding of the Relationship Between Environments, Epigenetic Modifications, and BehaviorSemantic proximity Read

Maternal High-Energy Diet during Pregnancy and Lactation Impairs Neurogenesis and Alters the Behavior of Adult Offspring in a Phenotype-Dependent Manner.Semantic proximity Read