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Article

Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes.

Journal of immunology research - 1 Jan 2015

de Oliveira Léa Campos, Goldberg Anna Carla, Marin Maria Lucia Carnevale, Schneidwind Karina Rosa, Frade Amanda Farage, Kalil Jorge, Miura Irene Kasue, Pugliese Renata Pereira Sustovich, Danesi Vera Lucia Baggio, Porta Gilda

Abstract excerpt

Pediatric autoimmune hepatitis (AIH) patients present hypergammaglobulinemia, periportal CD8(+) cytotoxic T cell infiltration, and cirrhosis. Autoantibody profile defines AIH types 1 and 2 in addition to strong association with HLA-DRB1. We previously detected increased IgE serum levels and sought to compare clinical and histological features according to IgE levels in AIH (n = 74, ages 1-14 years) patients....

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Source

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Identifiers

PMID: 26693492
DOI: 10.1155/2015/679813
PMCID: PMC4674601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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